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Home - Products - Cytoskeleton/Cell Adhesion Molecules - Microtubule/Tubulin - VERU-111 analogue 13f

VERU-111 analogue 13f

CAS No. ——

VERU-111 analogue 13f( —— )

Catalog No. M17045 CAS No. ——

VERU-111 analogue 13f is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    VERU-111 analogue 13f
  • Note
    Research use only, not for human use.
  • Brief Description
    VERU-111 analogue 13f is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities.
  • Description
    VERU-111 analogue 13f is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities; inhibits cell viability of human melanoma cell lines (A375, M14, and RPMI7951) with IC50 of 1-3 nM; VERU-111 analogue 13f is significantly more potent than VERU-111, exhibits a strong inhibitory effect on tumor growth in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    Microtubule/Tubulin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    373.368
  • Molecular Formula
    C21H15N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (2-(1H-indol-3-yl)-1H-imidazol-5-yl)(8-methoxybenzo[b][1,4]dioxin-6-yl)methanone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Wang Q, et al. J Med Chem. 2018 Aug 30. doi: 10.1021/acs.jmedchem.8b00827.
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